BindingDB logo
myBDB logout

BDBM50285759 5-alpha-hydroxyacid imidazolyl biphenyl sulfonyl urea analogue::CHEMBL315994

SMILES: CCCc1nc(SC)c(C(O)C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCc1ccccc1

InChI Key: InChIKey=ABGUYQYTMFLCKQ-UHFFFAOYNA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50285759   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin II receptor (AT-1) type-1


(RAT)
BDBM50285759
PNG
(5-alpha-hydroxyacid imidazolyl biphenyl sulfonyl u...)
Show SMILES CCCc1nc(SC)c(C(O)C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCc1ccccc1
Show InChI InChI=1/C30H32N4O6S2/c1-3-9-25-32-28(41-2)26(27(35)29(36)37)34(25)19-21-14-16-22(17-15-21)23-12-7-8-13-24(23)42(39,40)33-30(38)31-18-20-10-5-4-6-11-20/h4-8,10-17,27,35H,3,9,18-19H2,1-2H3,(H,36,37)(H2,31,33,38)
PDB

GoogleScholar
CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
n/an/a 6.60n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity at Angiotensin II Type 1 receptor in rat liver membrane by [125I]AII displacement.


Bioorg Med Chem Lett 5: 2611-2616 (1995)


Article DOI: 10.1016/0960-894X(95)00479-D
BindingDB Entry DOI: 10.7270/Q2GT5N57
More data for this
Ligand-Target Pair
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50285759
PNG
(5-alpha-hydroxyacid imidazolyl biphenyl sulfonyl u...)
Show SMILES CCCc1nc(SC)c(C(O)C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCc1ccccc1
Show InChI InChI=1/C30H32N4O6S2/c1-3-9-25-32-28(41-2)26(27(35)29(36)37)34(25)19-21-14-16-22(17-15-21)23-12-7-8-13-24(23)42(39,40)33-30(38)31-18-20-10-5-4-6-11-20/h4-8,10-17,27,35H,3,9,18-19H2,1-2H3,(H,36,37)(H2,31,33,38)
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
n/an/a 15n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity at Angiotensin II Type 2 receptor in rabbit uterus membrane by [125I]-AII displacement.


Bioorg Med Chem Lett 5: 2611-2616 (1995)


Article DOI: 10.1016/0960-894X(95)00479-D
BindingDB Entry DOI: 10.7270/Q2GT5N57
More data for this
Ligand-Target Pair