BDBM50286991 6-(3,4-Dichloro-phenyl)-4-hydroxy-3-(2-isopropyl-phenylsulfanyl)-pyran-2-one::CHEMBL13136

SMILES CC(C)c1ccccc1Sc1c(O)cc(oc1=O)-c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=CWJYRKNPQDOXNZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50286991   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50286991(6-(3,4-Dichloro-phenyl)-4-hydroxy-3-(2-isopropyl-p...)
Affinity DataIC50: 22nMpH: 4.7Assay Description:Inhibitory activity against purified HIV-1 protease (BH10) at a pH of 4.7 and a final enzyme concentration of 0.45-1.1 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article