BDBM50287130 2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phenyl-ethyl)-hydroxy-phosphinoyl]-propionylamino}-3-(1H-indol-3-yl)-propionic acid::CHEMBL281237

SMILES OC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1

InChI Key InChIKey=WWTBZEKOSBFBEM-VXRRSTMPSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50287130   

TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287130(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of neutral endopeptidase in human umbilical vein endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287130(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of neutral endopeptidase in human umbilical vein endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287130(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of neutral endopeptidase in human umbilical vein endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287130(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article