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BDBM50287207 (S)-1,3-Dibenzyl-4-(5-hydroxy-pentyl)-tetrahydro-thieno[3,4-d]imidazol-2-one::CHEMBL28619

SMILES: OCCCCC[C@@H]1SCC2C1N(Cc1ccccc1)C(=O)N2Cc1ccccc1

InChI Key: InChIKey=BYQGXFAPJUCLFA-KOENEWCDSA-N

Data: 1 KI

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50287207   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Human immunodeficiency virus type 1 protease


(Human immunodeficiency virus type 1)
BDBM50287207
PNG
((S)-1,3-Dibenzyl-4-(5-hydroxy-pentyl)-tetrahydro-t...)
Show SMILES OCCCCC[C@@H]1SCC2C1N(Cc1ccccc1)C(=O)N2Cc1ccccc1
Show InChI InChI=1S/C24H30N2O2S/c27-15-9-3-8-14-22-23-21(18-29-22)25(16-19-10-4-1-5-11-19)24(28)26(23)17-20-12-6-2-7-13-20/h1-2,4-7,10-13,21-23,27H,3,8-9,14-18H2/t21?,22-,23?/m0/s1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
1.03E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against HIV protease enzyme.


Bioorg Med Chem Lett 6: 1371-1374 (1996)


Article DOI: 10.1016/0960-894X(96)00233-8
BindingDB Entry DOI: 10.7270/Q2FF3SB8
More data for this
Ligand-Target Pair