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BDBM50287277 CHEMBL4170753::US10759787, Example 18::US11059811, Example 18

SMILES: CCN(C1CCOCC1)c1cc2occc2c(C(=O)NCc2c(OC)cc(C)[nH]c2=O)c1C

InChI Key: InChIKey=IBJQZJITWHHCOE-UHFFFAOYSA-N

Data: 5 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50287277
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone-lysine N-methyltransferase EZH2 [A677G] (Human)	BDBM50287277 (CHEMBL4170753 \| US10759787, Example 18 \| US1105981...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 [Y641F] (Human)	BDBM50287277 (CHEMBL4170753 \| US10759787, Example 18 \| US1105981...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 [A677G] (Human)	BDBM50287277 (CHEMBL4170753 \| US10759787, Example 18 \| US1105981...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 [Y641F] (Human)	BDBM50287277 (CHEMBL4170753 \| US10759787, Example 18 \| US1105981...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Histone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH1/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2 (Human)	BDBM50287277 (CHEMBL4170753 \| US10759787, Example 18 \| US1105981...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair