BDBM50287332 1N-[4-cyclopropylmethyl-10-hydroxy-(13R,14R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-yl]-2-chloroacrylamide::CHEMBL289426

SMILES Oc1ccc2CC3C4CC[C@@H](NC(=O)C(Cl)=C)[C@@H]5Oc1c2C45CCN3CC1CC1

InChI Key InChIKey=UDQTWCPWUCXLPN-CUUMVBPWSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50287332   

TargetDelta-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287332(1N-[4-cyclopropylmethyl-10-hydroxy-(13R,14R)-12-ox...)
Affinity DataIC50:  0.530nMAssay Description:Compound was tested for Inhibition of 9 (1nM) binding to Opioid receptor delta 1 from bovine striatal MembranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKappa-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287332(1N-[4-cyclopropylmethyl-10-hydroxy-(13R,14R)-12-ox...)
Affinity DataIC50:  1.5nMAssay Description:Compound was tested for Inhibition of [3H]-DPDPE (0.2 nM) binding to Opioid receptor kappa 1 from bovine striatal MembranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMu-type opioid receptor(CALF)
TBA

Curated by ChEMBL
LigandPNGBDBM50287332(1N-[4-cyclopropylmethyl-10-hydroxy-(13R,14R)-12-ox...)
Affinity DataIC50:  0.210nMAssay Description:Compound was tested for Inhibition of [3H]-DAMGO (0.25 nM) binding to mu receptor from bovine striatal membranesMore data for this Ligand-Target Pair
In DepthDetails Article