BDBM50287517 3-(2,6-Diisopropyl-phenyl)-1-(2-dodecyl-2H-tetrazol-5-yl)-1-phenyl-urea::CHEMBL52443

SMILES CCCCCCCCCCCCn1nnc(n1)N(C(=O)Nc1c(cccc1C(C)C)C(C)C)c1ccccc1

InChI Key InChIKey=BDTOUKJDASDLPQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50287517   

TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50287517(3-(2,6-Diisopropyl-phenyl)-1-(2-dodecyl-2H-tetrazo...)
Affinity DataIC50:  47nMAssay Description:Liver Acyl coenzyme A:cholesterol acyltransferase inhibitory activity was determined in vitro using [1-14C]-oleolyl-CoA and microsomes isolated from ...More data for this Ligand-Target Pair
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TargetSterol O-acyltransferase 1(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50287517(3-(2,6-Diisopropyl-phenyl)-1-(2-dodecyl-2H-tetrazo...)
Affinity DataIC50:  240nMAssay Description:Compound was tested for its ability to penetrate the cell wall and inhibit macrophage ACAT in cell culture using murine IC-21 macrophages (MAI)More data for this Ligand-Target Pair
In DepthDetails Article