BDBM50287518 1-(2-Dodecyl-2H-tetrazol-5-yl)-1-phenyl-3-(2,4,6-trimethoxy-phenyl)-urea::CHEMBL49524

SMILES CCCCCCCCCCCCn1nnc(n1)N(C(=O)Nc1c(OC)cc(OC)cc1OC)c1ccccc1

InChI Key InChIKey=VGOIOMRNPIXNIH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50287518   

TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50287518(1-(2-Dodecyl-2H-tetrazol-5-yl)-1-phenyl-3-(2,4,6-t...)
Affinity DataIC50:  61nMAssay Description:Liver ACAT inhibitory activity was determined in vitro using [1-14C]-oleolyl-CoA and microsomes isolated from the livers of cholesterol fed ratsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50287518(1-(2-Dodecyl-2H-tetrazol-5-yl)-1-phenyl-3-(2,4,6-t...)
Affinity DataIC50:  890nMAssay Description:Compound was tested for its ability to penetrate the cell wall and inhibit macrophage ACAT in cell culture using murine IC-21 macrophages (MAI)More data for this Ligand-Target Pair
In DepthDetails Article