BDBM50288023 CHEMBL77962::N-(4-Bromo-3-methyl-isoxazol-5-yl)-2,4,6-trimethyl-benzenesulfonamide

SMILES Cc1noc(NS(=O)(=O)c2c(C)cc(C)cc2C)c1Br

InChI Key InChIKey=ITWYSOIYYHELQO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50288023   

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288023(N-(4-Bromo-3-methyl-isoxazol-5-yl)-2,4,6-trimethyl...)
Affinity DataIC50: 5.90E+3nMAssay Description:Binding affinity against human ETA receptor in TE 671(ATCC# HTB 139) cell membrane preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288023(N-(4-Bromo-3-methyl-isoxazol-5-yl)-2,4,6-trimethyl...)
Affinity DataIC50: 4.60E+4nMAssay Description:Binding affinity against human ETB receptor in transfected COS 7 cell membrane preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article