BDBM50288028 CHEMBL78952::N-(3,4-Dimethyl-isoxazol-5-yl)-4-methyl-benzenesulfonamide

SMILES Cc1noc(NS(=O)(=O)c2ccc(C)cc2)c1C

InChI Key InChIKey=JGXIRMJIDPMUJD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50288028   

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288028(N-(3,4-Dimethyl-isoxazol-5-yl)-4-methyl-benzenesul...)
Affinity DataIC50: 4.20E+3nMAssay Description:Binding affinity against human Endothelin A receptor in TE 671(ATCC# HTB 139) cell membrane preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288028(N-(3,4-Dimethyl-isoxazol-5-yl)-4-methyl-benzenesul...)
Affinity DataIC50: 1.50E+4nMAssay Description:Binding affinity against human Endothelin B receptor in transfected COS 7 cell membrane preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article