BDBM50288204 (2S,3S)-3-Carboxymethyl-azetidine-2-carboxylic acid::CHEMBL314690

SMILES OC(=O)C[C@H]1CN[C@@H]1C(O)=O

InChI Key InChIKey=FQUPICCTRPWMDZ-UCORVYFPSA-N

Data  7 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50288204   

TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288204((2S,3S)-3-Carboxymethyl-azetidine-2-carboxylic aci...)
Affinity DataIC50: >3.00E+5nMAssay Description:Compound was tested for its agonist activity against mGluR 6 receptor in CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288204((2S,3S)-3-Carboxymethyl-azetidine-2-carboxylic aci...)
Affinity DataIC50: >6.00E+5nMAssay Description:Compound was tested for its antagonist activity against mGluR 2 receptor in CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288204((2S,3S)-3-Carboxymethyl-azetidine-2-carboxylic aci...)
Affinity DataEC50:  2.10E+5nMAssay Description:Compound was tested for its agonist activity against mGluR1a receptor in CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50288204((2S,3S)-3-Carboxymethyl-azetidine-2-carboxylic aci...)
Affinity DataIC50: >6.60E+5nMAssay Description:Compound was tested in vitro for binding affinity against Ionotropic glutamate receptor AMPA, using [3H]-TCP as the radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288204((2S,3S)-3-Carboxymethyl-azetidine-2-carboxylic aci...)
Affinity DataEC50: >6.00E+5nMAssay Description:Compound was tested for its antagonist activity against mGluR 6 receptor in CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288204((2S,3S)-3-Carboxymethyl-azetidine-2-carboxylic aci...)
Affinity DataEC50:  1.05E+5nMAssay Description:Compound was tested for its agonist activity against mGluR 5a receptor in CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50288204((2S,3S)-3-Carboxymethyl-azetidine-2-carboxylic aci...)
Affinity DataIC50:  3.15E+5nMAssay Description:Compound was tested in vitro for binding affinity against mGluR4a metabotropic glutamate receptor, using [3H]-L-AP4 as the radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50288204((2S,3S)-3-Carboxymethyl-azetidine-2-carboxylic aci...)
Affinity DataIC50:  1.20E+4nMAssay Description:Compound was tested in vitro for binding affinity against mGluR1a metabotropic glutamate receptor, using [3H]-glutamate as the radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288204((2S,3S)-3-Carboxymethyl-azetidine-2-carboxylic aci...)
Affinity DataIC50: >3.00E+5nMAssay Description:Compound was tested for its agonist activity against mGluR 2 receptor in CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50288204((2S,3S)-3-Carboxymethyl-azetidine-2-carboxylic aci...)
Affinity DataIC50:  700nMAssay Description:Compound was tested in vitro for binding affinity against Ionotropic glutamate receptor kainate using [3H]-kainate as the radioligand.More data for this Ligand-Target Pair
In DepthDetails Article