BDBM50289291 2-Hydroxy-methylolanzapine::CHEMBL100454::[10-(4-Methyl-piperazin-1-yl)-4H-3-thia-4,9-diaza-benzo[f]azulen-2-yl]-methanol

SMILES: CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(CO)cc12

InChI Key: InChIKey=FPDIERBPQFAFSI-UHFFFAOYSA-N

Data: 8 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50289291   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50289291 ([10-(4-Methyl-piperazin-1-yl)-4H-3-thia-4,9-diaza-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM50289291 ([10-(4-Methyl-piperazin-1-yl)-4H-3-thia-4,9-diaza-...) Show SMILES Show InChI	GoogleScholar	UniChem		6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Human)	BDBM50289291 ([10-(4-Methyl-piperazin-1-yl)-4H-3-thia-4,9-diaza-...) Show SMILES Show InChI	GoogleScholar	UniChem		12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Serotonin 2 (5-HT2) receptor (Human)	BDBM50289291 ([10-(4-Methyl-piperazin-1-yl)-4H-3-thia-4,9-diaza-...) Show SMILES Show InChI	GoogleScholar	UniChem		18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50289291 ([10-(4-Methyl-piperazin-1-yl)-4H-3-thia-4,9-diaza-...) Show SMILES Show InChI	GoogleScholar	UniChem		22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A) dopamine receptor (Human)	BDBM50289291 ([10-(4-Methyl-piperazin-1-yl)-4H-3-thia-4,9-diaza-...) Show SMILES Show InChI	GoogleScholar	UniChem		66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (Human)	BDBM50289291 ([10-(4-Methyl-piperazin-1-yl)-4H-3-thia-4,9-diaza-...) Show SMILES Show InChI	GoogleScholar	UniChem		501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Human)	BDBM50289291 ([10-(4-Methyl-piperazin-1-yl)-4H-3-thia-4,9-diaza-...) Show SMILES Show InChI	GoogleScholar	UniChem		783	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-1/Beta-2/Beta-3 adrenergic receptor (Human)	BDBM50289291 ([10-(4-Methyl-piperazin-1-yl)-4H-3-thia-4,9-diaza-...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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