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BDBM50289633 1-[(R)-4-(Pyrrolidine-1-carbonyl)-thiazolidin-3-yl]-tetradecan-1-one::CHEMBL47926

SMILES: CCCCCCCCCCCCCC(=O)N1CSC[C@H]1C(=O)N1CCCC1

InChI Key: InChIKey=VPBRSKIHWKRPHA-FQEVSTJZSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50289633   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prolyl endopeptidase


(Rattus norvegicus)
BDBM50289633
PNG
(1-[(R)-4-(Pyrrolidine-1-carbonyl)-thiazolidin-3-yl...)
Show SMILES CCCCCCCCCCCCCC(=O)N1CSC[C@H]1C(=O)N1CCCC1
Show InChI InChI=1S/C22H40N2O2S/c1-2-3-4-5-6-7-8-9-10-11-12-15-21(25)24-19-27-18-20(24)22(26)23-16-13-14-17-23/h20H,2-19H2,1H3/t20-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 80n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against rat brain Prolyl endopeptidase (PEP)


Bioorg Med Chem Lett 7: 1701-1704 (1997)


Article DOI: 10.1016/S0960-894X(97)00295-3
BindingDB Entry DOI: 10.7270/Q2BP02SR
More data for this
Ligand-Target Pair