BDBM50289703 Lumacaftor::VRT 826809::VRT-826809::VX 809::VX-809

SMILES: Cc1ccc(NC(=O)C2(CC2)c2ccc3OC(F)(F)Oc3c2)nc1-c1cccc(c1)C(O)=O

InChI Key: InChIKey=UFSKUSARDNFIRC-UHFFFAOYSA-N

Data: 2 IC50  2 Kd  4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50289703   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cystic fibrosis transmembrane conductance regulator (Human)	BDBM50289703 (Lumacaftor | VRT 826809 | VRT-826809 | VX 809 | VX...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Human)	BDBM50289703 (Lumacaftor | VRT 826809 | VRT-826809 | VX 809 | VX...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.57E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Human)	BDBM50289703 (Lumacaftor | VRT 826809 | VRT-826809 | VX 809 | VX...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Human)	BDBM50289703 (Lumacaftor | VRT 826809 | VRT-826809 | VX 809 | VX...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cytochrome P450 2C8 (Human)	BDBM50289703 (Lumacaftor | VRT 826809 | VRT-826809 | VX 809 | VX...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Human)	BDBM50289703 (Lumacaftor | VRT 826809 | VRT-826809 | VX 809 | VX...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Human)	BDBM50289703 (Lumacaftor | VRT 826809 | VRT-826809 | VX 809 | VX...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	7.28E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Human)	BDBM50289703 (Lumacaftor | VRT 826809 | VRT-826809 | VX 809 | VX...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.78E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair