BDBM50289741 CHEMBL418106::[3-Oxo-4-(5-trifluoromethyl-benzothiazol-2-ylmethyl)-5,6-dihydro-3H-benzo[h]cinnolin-2-yl]-acetic acid

SMILES OC(=O)Cn1nc-2c(CCc3ccccc-23)c(Cc2nc3cc(ccc3s2)C(F)(F)F)c1=O

InChI Key InChIKey=WDSIURMLIZMUHJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50289741   

TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
TBA

Curated by ChEMBL
LigandPNGBDBM50289741(CHEMBL418106 | [3-Oxo-4-(5-trifluoromethyl-benzoth...)
Affinity DataIC50:  150nMAssay Description:Functional antagonism against ETA receptor in rat aortic rings expressed as pA2 valueMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
TBA

Curated by ChEMBL
LigandPNGBDBM50289741(CHEMBL418106 | [3-Oxo-4-(5-trifluoromethyl-benzoth...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibitory activity of compound against modified enzyme form of S-glutathionyl Aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails Article