BDBM50289879 CHEMBL62205::[(S)-2-(1H-Indol-3-yl)-1-methyl-1-phenethylcarbamoyl-ethyl]-carbamic acid adamantan-2-yl ester

SMILES C[C@@](Cc1c[nH]c2ccccc12)(NC(=O)OC1C2CC3CC(C2)CC1C3)C(=O)NCCc1ccccc1

InChI Key InChIKey=RGFJPHVCLXSEHE-GYSLRPEDSA-N

Data  2 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50289879   

TargetGastrin/cholecystokinin type B receptor(MOUSE)
Parke-Davis Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50289879(CHEMBL62205 | [(S)-2-(1H-Indol-3-yl)-1-methyl-1-ph...)
Affinity DataKi:  21nMAssay Description:Cholecystokinin type B receptor binding assay performed on homogenized cerebral cortex from male mouseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(MOUSE)
Parke-Davis Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50289879(CHEMBL62205 | [(S)-2-(1H-Indol-3-yl)-1-methyl-1-ph...)
Affinity DataKi:  21.4nMAssay Description:Cholecystokinin type B receptor binding assay performed on homogenized cerebral cortex from male mouseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(MOUSE)
Parke-Davis Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50289879(CHEMBL62205 | [(S)-2-(1H-Indol-3-yl)-1-methyl-1-ph...)
Affinity DataIC50:  32nMAssay Description:Binding affinity towards Cholecystokinin type B receptor in mouse cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(MOUSE)
Parke-Davis Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50289879(CHEMBL62205 | [(S)-2-(1H-Indol-3-yl)-1-methyl-1-ph...)
Affinity DataIC50:  32nMAssay Description:Inhibition of binding of [125I]- Bolton-Hunter labeled CCK-8 to CCK-B receptor in the mouse cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCholecystokinin receptor type A(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50289879(CHEMBL62205 | [(S)-2-(1H-Indol-3-yl)-1-methyl-1-ph...)
Affinity DataIC50:  650nMAssay Description:Inhibition of binding of [125I]- Bolton-Hunter labeled CCK-8 to CCK-A receptor in the rat pancreasMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCholecystokinin receptor type A(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50289879(CHEMBL62205 | [(S)-2-(1H-Indol-3-yl)-1-methyl-1-ph...)
Affinity DataIC50:  377nMAssay Description:In vitro inhibition of [125I]- Bolton Hunter CCK-8 to Cholecystokinin type A receptor in the rat pancreas.More data for this Ligand-Target Pair
In DepthDetails Article
TargetGastrin/cholecystokinin type B receptor(MOUSE)
Parke-Davis Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50289879(CHEMBL62205 | [(S)-2-(1H-Indol-3-yl)-1-methyl-1-ph...)
Affinity DataIC50:  48nMAssay Description:In vitro inhibition of [125I]- Bolton Hunter CCK-8 binding to Cholecystokinin type B receptor in the mouse cerebral cortex.More data for this Ligand-Target Pair
In DepthDetails Article
TargetCholecystokinin receptor type A(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50289879(CHEMBL62205 | [(S)-2-(1H-Indol-3-yl)-1-methyl-1-ph...)
Affinity DataIC50:  650nMAssay Description:Compound was evaluated for the binding affinity towards rat pancreatic Cholecystokinin type A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed