BDBM50290297 1-{2-[(R)-3-(3,4-Dichloro-phenyl)-1-(3,4,5-trimethoxy-benzoyl)-pyrrolidin-3-yl]-ethyl}-4-phenyl-piperidine-4-carboxylic acid amide; hydrochloride::CHEMBL539021::MDL 103,392A racemate

SMILES COc1cc(cc(OC)c1OC)C(=O)N1CC[C@@](CCN2CCC(CC2)(C(N)=O)c2ccccc2)(C1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=WZMVQZJKOVPVGZ-XIFFEERXSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50290297   

TargetSubstance-P receptor(GUINEA PIG)
Hoechst Marion Roussel

Curated by PDSP Ki Database
LigandPNGBDBM50290297(1-{2-[(R)-3-(3,4-Dichloro-phenyl)-1-(3,4,5-trimeth...)
Affinity DataKi:  5.88nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by PDSP Ki Database
LigandPNGBDBM50290297(1-{2-[(R)-3-(3,4-Dichloro-phenyl)-1-(3,4,5-trimeth...)
Affinity DataKi:  7.07nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by PDSP Ki Database
LigandPNGBDBM50290297(1-{2-[(R)-3-(3,4-Dichloro-phenyl)-1-(3,4,5-trimeth...)
Affinity DataKi:  21nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNeuromedin-K receptor(GUINEA PIG)
Hoechst Marion Roussel

Curated by PDSP Ki Database
LigandPNGBDBM50290297(1-{2-[(R)-3-(3,4-Dichloro-phenyl)-1-(3,4,5-trimeth...)
Affinity DataKi:  54.3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSubstance-P receptor(GUINEA PIG)
Hoechst Marion Roussel

Curated by PDSP Ki Database
LigandPNGBDBM50290297(1-{2-[(R)-3-(3,4-Dichloro-phenyl)-1-(3,4,5-trimeth...)
Affinity DataIC50:  3.10nMAssay Description:Binding affinity for NK1 receptor in guinea pig lung was determined by using [125 I]-Bolton Hunter labeled SPMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-K receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290297(1-{2-[(R)-3-(3,4-Dichloro-phenyl)-1-(3,4,5-trimeth...)
Affinity DataIC50:  8.40nMAssay Description:Binding affinity for NK2 receptor in HSKR-1 cells was determined by using [125 I ]-Iodohistidyl NKA.More data for this Ligand-Target Pair
In DepthDetails Article