BDBM50290422 4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide::4-[(4-METHYLPIPERAZIN-1-YL)METHYL]-N-{3-[(4-PYRIDIN-3-YLPYRIMIDIN-2-YL)AMINO]PHENYL}BENZAMIDE::CHEMBL56904

SMILES: CN1CCN(Cc2ccc(cc2)C(=O)Nc2cccc(Nc3nccc(n3)-c3cccnc3)c2)CC1

InChI Key: InChIKey=JHMBUEWQJDGKGS-UHFFFAOYSA-N

Data: 1 KI  11 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50290422   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Breakpoint cluster region protein (Mouse)	BDBM50290422 (4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor beta (Mouse)	BDBM50290422 (4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50290422 (4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-dependent protein kinase catalytic subunit gamma (Human)	BDBM50290422 (4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50290422 (4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50290422 (4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-dependent protein kinase catalytic subunit alpha/beta/gamma (Human)	BDBM50290422 (4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.75E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM50290422 (4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ABL1 (Human)	BDBM50290422 (4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Human)	BDBM50290422 (4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
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Breakpoint cluster region protein/Tyrosine-protein kinase ABL1 (Human)	BDBM50290422 (4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase SYK (Human)	BDBM50290422 (4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-...) Show SMILES Show InChI	GoogleScholar	UniChem		160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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