BindingDB PrimarySearch

BDBM50048392 2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one::BUPROPION::BUPROPION HYDROCHLORIDE::CHEMBL894::US9944618, Compound ID No. 176

SMILES: CC(NC(C)(C)C)C(=O)c1cccc(Cl)c1

InChI Key: InChIKey=SNPPWIUOZRMYNY-UHFFFAOYSA-N

Data: 66 KI 47 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 113 hits for monomerid = 50048392
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	6.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 1A1 (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 1A4 (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.52E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 1-6 (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 2B7 (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 2B10 (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	8.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 4 (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 2 (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 3 (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	658	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-4 (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-2 (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	945	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	443	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	658	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histamine H1 receptor (Rat)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	173	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM50048392 (BUPROPION HYDROCHLORIDE \| CHEMBL894 \| 2-(tert-buty...) Show SMILES Show InChI	GoogleScholar	UniChem	372	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair

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