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BDBM50290563 2-[[6-(4-Bromo-benzylamino)-9-isopropyl-9H-purin-2-yl]-(2-hydroxy-ethyl)-amino]-ethanol::CHEMBL92544

SMILES: CC(C)n1cnc2c(NCc3ccc(Br)cc3)nc(nc12)N(CCO)CCO

InChI Key: InChIKey=KXWPJLNSYQKTCM-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50290563   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CDK2/Cyclin E/G1/S-specific cyclin E2


(Homo sapiens (Human))
BDBM50290563
PNG
(2-[[6-(4-Bromo-benzylamino)-9-isopropyl-9H-purin-2...)
Show SMILES CC(C)n1cnc2c(NCc3ccc(Br)cc3)nc(nc12)N(CCO)CCO
Show InChI InChI=1S/C19H25BrN6O2/c1-13(2)26-12-22-16-17(21-11-14-3-5-15(20)6-4-14)23-19(24-18(16)26)25(7-9-27)8-10-28/h3-6,12-13,27-28H,7-11H2,1-2H3,(H,21,23,24)
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Similars

Article
n/an/a 2.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin E


Bioorg Med Chem Lett 7: 2697-2702 (1997)


Article DOI: 10.1016/S0960-894X(97)10076-2
BindingDB Entry DOI: 10.7270/Q2FJ2H8Q
More data for this
Ligand-Target Pair