BDBM50290702 CHEMBL322194::[3-(2-{4-[1-(2-Ethoxy-ethyl)-1H-benzoimidazole-2-carbonyl]-piperidin-1-yl}-ethyl)-3-phenyl-pyrrolidin-1-yl]-(3,4,5-trimethoxy-phenyl)-methanone

SMILES CCOCCn1c(nc2ccccc12)C(=O)C1CCN(CCC2(CCN(C2)C(=O)c2cc(OC)c(OC)c(OC)c2)c2ccccc2)CC1

InChI Key InChIKey=ADZSGFZICHOKOJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50290702   

TargetSubstance-P receptor(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50290702(CHEMBL322194 | [3-(2-{4-[1-(2-Ethoxy-ethyl)-1H-ben...)
Affinity DataIC50:  26nMAssay Description:Antagonism of the guinea pig tachykinin NK1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetHistamine H1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290702(CHEMBL322194 | [3-(2-{4-[1-(2-Ethoxy-ethyl)-1H-ben...)
Affinity DataIC50:  381nMAssay Description:Antagonism of the human histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetHistamine H1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290702(CHEMBL322194 | [3-(2-{4-[1-(2-Ethoxy-ethyl)-1H-ben...)
Affinity DataIC50:  6.40nMAssay Description:Antagonistic activity against histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50290702(CHEMBL322194 | [3-(2-{4-[1-(2-Ethoxy-ethyl)-1H-ben...)
Affinity DataIC50:  7.60nMAssay Description:Antagonistic activity against Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article