BDBM50290834 4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline::CHEMBL327300

SMILES COc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cc1OC

InChI Key InChIKey=ZQSHUGGLESWJFP-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50290834   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of epidermal growth factor receptor (EGF-R)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInsulin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of insulin beta-R in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MAPKKMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of c-SRCMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Cdc2More data for this Ligand-Target Pair
In DepthDetails Article
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Fibroblast growth factor receptor in NIH 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of epidermal growth factor receptor (EGF-R) in A431 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50:  30nMAssay Description:Inhibition of Platelet-derived growth factor receptor beta (PDGF beta-R)More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50:  70nMAssay Description:Inhibition of platelet-derived growth factor receptor (PDGF-R) in human aortic smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMitogen-activated protein kinase 1/3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of platelet-derived growth factor receptor (PDGF-R) from NIH 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50:  150nMAssay Description:Inhibition of epidermal growth factor receptor (EGF-R) in A431 cells.More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Protein kinase AMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor beta(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50:  130nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article