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BDBM50290837 4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinazoline::CHEMBL431818

SMILES: COc1ccc(Oc2ncnc3cc(OC)c(OC)cc23)cc1OC

InChI Key: InChIKey=GITRKILOUAEMSZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50290837   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (human))
BDBM50290837
PNG
(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinazolin...)
Show SMILES COc1ccc(Oc2ncnc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C18H18N2O5/c1-21-14-6-5-11(7-15(14)22-2)25-18-12-8-16(23-3)17(24-4)9-13(12)19-10-20-18/h5-10H,1-4H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a>1.00E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of epidermal growth factor receptor (EGF-R) autophosphorylation in A431 cells


Bioorg Med Chem Lett 7: 2935-2940 (1997)


Article DOI: 10.1016/S0960-894X(97)10117-2
BindingDB Entry DOI: 10.7270/Q20Z738R
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor (PDGFr)


(Rattus norvegicus)
BDBM50290837
PNG
(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinazolin...)
Show SMILES COc1ccc(Oc2ncnc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C18H18N2O5/c1-21-14-6-5-11(7-15(14)22-2)25-18-12-8-16(23-3)17(24-4)9-13(12)19-10-20-18/h5-10H,1-4H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 570n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.


Bioorg Med Chem Lett 7: 2935-2940 (1997)


Article DOI: 10.1016/S0960-894X(97)10117-2
BindingDB Entry DOI: 10.7270/Q20Z738R
More data for this
Ligand-Target Pair