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BDBM50290848 6,7-Dimethoxy-4-(2-methoxy-phenoxy)-quinoline::CHEMBL415501

SMILES: COc1ccccc1Oc1ccnc2cc(OC)c(OC)cc12

InChI Key: InChIKey=ZTLZYKICAWTOKI-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50290848   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor receptor (PDGFr)


(Rattus norvegicus)
BDBM50290848
PNG
(6,7-Dimethoxy-4-(2-methoxy-phenoxy)-quinoline | CH...)
Show SMILES COc1ccccc1Oc1ccnc2cc(OC)c(OC)cc12
Show InChI InChI=1S/C18H17NO4/c1-20-15-6-4-5-7-16(15)23-14-8-9-19-13-11-18(22-3)17(21-2)10-12(13)14/h4-11H,1-3H3
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Similars

Article
n/an/a 600n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.


Bioorg Med Chem Lett 7: 2935-2940 (1997)


Article DOI: 10.1016/S0960-894X(97)10117-2
BindingDB Entry DOI: 10.7270/Q20Z738R
More data for this
Ligand-Target Pair