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BDBM50290852 4-(3,5-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline::CHEMBL101733

SMILES: COc1cc(OC)cc(Oc2ccnc3cc(OC)c(OC)cc23)c1

InChI Key: InChIKey=RNXKKASQCMYWCJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50290852   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor receptor (PDGFr)


(Rattus norvegicus)
BDBM50290852
PNG
(4-(3,5-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Show SMILES COc1cc(OC)cc(Oc2ccnc3cc(OC)c(OC)cc23)c1
Show InChI InChI=1S/C19H19NO5/c1-21-12-7-13(22-2)9-14(8-12)25-17-5-6-20-16-11-19(24-4)18(23-3)10-15(16)17/h5-11H,1-4H3
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PC cid
PC sid
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Similars

Article
n/an/a 5.50E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.


Bioorg Med Chem Lett 7: 2935-2940 (1997)


Article DOI: 10.1016/S0960-894X(97)10117-2
BindingDB Entry DOI: 10.7270/Q20Z738R
More data for this
Ligand-Target Pair