BDBM50290882 CHEMBL102521::N-hydroxyglycine derivative

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#8]-c1cccc(-[#6]-[#7]-[#6](=O)-[#7](-[#8])C([#6])([#6])[#6](-[#8-])=O)c1

InChI Key InChIKey=XLKKVTPYICOPGS-UHFFFAOYSA-M

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50290882   

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290882(N-hydroxyglycine derivative | CHEMBL102521)
Affinity DataIC50: 170nMAssay Description:The compound was tested for inhibition of purified rat hepatic squalene synthase in the presence of 1.2 mM NADPH and 1.0 mM inorganic pyrophosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290882(N-hydroxyglycine derivative | CHEMBL102521)
Affinity DataIC50: 230nMAssay Description:Inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290882(N-hydroxyglycine derivative | CHEMBL102521)
Affinity DataIC50: 950nMAssay Description:The compound was tested for inhibition of purified rat hepatic squalene synthase in the presence of 1.2 mM NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290882(N-hydroxyglycine derivative | CHEMBL102521)
Affinity DataIC50: 5.70E+4nMAssay Description:The compound was tested for inhibition of purified rat hepatic squalene synthase in the presence of 0.025 mM NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article