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BDBM50291593 1'-(4-tetrahydro-1H-1-pyrrolyl-2-butynyl)spiro[2,3-dihydro-1H-indene-1,3'-(tetrahydro-1'H-pyrrole)]-2',5'-dione::CHEMBL177259

SMILES: O=C1CC2(CCc3ccccc23)C(=O)N1CC#CCN1CCCC1

InChI Key: InChIKey=UKLDWQAFHBMKNS-UHFFFAOYNA-N

Data: 2 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50291593   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50291593
PNG
(1'-(4-tetrahydro-1H-1-pyrrolyl-2-butynyl)spiro[2,3...)
Show SMILES O=C1CC2(CCc3ccccc23)C(=O)N1CC#CCN1CCCC1
Show InChI InChI=1/C20H22N2O2/c23-18-15-20(10-9-16-7-1-2-8-17(16)20)19(24)22(18)14-6-5-13-21-11-3-4-12-21/h1-2,7-8H,3-4,9-15H2
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PC cid
PC sid
UniChem

Similars

Article
1.59E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]pirenzepine from muscarinic M1 receptor of rat cortex homogenates.


Bioorg Med Chem Lett 7: 979-984 (1997)


Article DOI: 10.1016/S0960-894X(97)00143-1
BindingDB Entry DOI: 10.7270/Q2N29XFM
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(RAT)
BDBM50291593
PNG
(1'-(4-tetrahydro-1H-1-pyrrolyl-2-butynyl)spiro[2,3...)
Show SMILES O=C1CC2(CCc3ccccc23)C(=O)N1CC#CCN1CCCC1
Show InChI InChI=1/C20H22N2O2/c23-18-15-20(10-9-16-7-1-2-8-17(16)20)19(24)22(18)14-6-5-13-21-11-3-4-12-21/h1-2,7-8H,3-4,9-15H2
PDB

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KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
>1.00E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]QNB (quinuclidinyl benzylate) from muscarinic M2 receptor of rat heart homogenates.


Bioorg Med Chem Lett 7: 979-984 (1997)


Article DOI: 10.1016/S0960-894X(97)00143-1
BindingDB Entry DOI: 10.7270/Q2N29XFM
More data for this
Ligand-Target Pair