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BDBM50291686 (R)-(3-Chloro-phenyl)-((R)-1-methyl-piperidin-2-yl)-acetic acid methyl ester::CHEMBL19869

SMILES: COC(=O)[C@@H]([C@H]1CCCCN1C)c1cccc(Cl)c1

InChI Key: InChIKey=CCEXSBJFYDQYOG-ZIAGYGMSSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50291686   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium-dependent dopamine transporter


(Rattus norvegicus (rat))
BDBM50291686
PNG
((R)-(3-Chloro-phenyl)-((R)-1-methyl-piperidin-2-yl...)
Show SMILES COC(=O)[C@@H]([C@H]1CCCCN1C)c1cccc(Cl)c1
Show InChI InChI=1S/C15H20ClNO2/c1-17-9-4-3-8-13(17)14(15(18)19-2)11-6-5-7-12(16)10-11/h5-7,10,13-14H,3-4,8-9H2,1-2H3/t13-,14-/m1/s1
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Similars

Article
n/an/a 161n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
The compound was tested for its affinity at the rat striatal dopamine transporter by the displacement of [3H]WIN-35428


Bioorg Med Chem Lett 7: 1213-1218 (1997)


Article DOI: 10.1016/S0960-894X(97)00193-5
BindingDB Entry DOI: 10.7270/Q27S7P87
More data for this
Ligand-Target Pair