BDBM50291707 (S)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid 2-fluoro-ethyl ester::CHEMBL347021
SMILES COc1ccc(cc1)[P@@](=O)(OCCF)N1Cc2ccccc2C[C@@H]1C(=O)NO
InChI Key InChIKey=KFUADVZPCULIED-KWMCUTETSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50291707
Affinity DataKi: 9.10nMAssay Description:Inhibition of Matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
Affinity DataKi: 9.10nMAssay Description:Inhibitory constant against recombinant human stromelysin-1 (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibitory constant against recombinant human gelatinase B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of Matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibitory constant against recombinant human Matrix metalloproteinase-1More data for this Ligand-Target Pair
Affinity DataKi: >650nMAssay Description:Inhibitory constant against recombinant human Matrix metalloproteinase-1More data for this Ligand-Target Pair
Affinity DataKi: 686nMAssay Description:Inhibitory constant against recombinant human Matrix metalloproteinase-1More data for this Ligand-Target Pair
Affinity DataKi: >800nMAssay Description:Inhibitory constant against recombinant human stromelysin-1 (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Organon K.K.
Curated by ChEMBL
Organon K.K.
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of heparin-binding epidermal growth factor (HB-EGF) sheddingMore data for this Ligand-Target Pair
Affinity DataIC50: 470nMAssay Description:In vitro amphiregulin shedding inhibitionMore data for this Ligand-Target Pair