BindingDB logo
myBDB logout

BDBM50292523 2-(3,4-dihydroxyphenyl)ethene-1,1,2-tricarbonitrile::CHEMBL474267::RG-50810

SMILES: [#8]-c1ccc(cc1-[#8])-[#6](\C#N)=[#6](\C#N)C#N

InChI Key: InChIKey=ORMGLUKCDQMGKV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50292523   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (human))
BDBM50292523
PNG
(2-(3,4-dihydroxyphenyl)ethene-1,1,2-tricarbonitril...)
Show SMILES Oc1ccc(cc1O)C(C#N)=C(C#N)C#N
Show InChI InChI=1S/C11H5N3O2/c12-4-8(5-13)9(6-14)7-1-2-10(15)11(16)3-7/h1-3,15-16H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of EGFR in human A431 cells


J Nat Prod 55: 1529-1560 (1992)


Article DOI: 10.1021/np50089a001
BindingDB Entry DOI: 10.7270/Q2J966CC
More data for this
Ligand-Target Pair