BDBM50292629 (23S)-25-dehydro-2-methylene-19-nor-1alpha-hydroxyvitaminD3-26,23-lactone::(S)-5-((R)-2-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-dihydroxy-4-methylenecyclohexylidene)ethylidene)-7a-methyl-octahydro-1H-inden-1-yl)propyl)-3-methylene-dihydrofuran-2(3H)-one::CHEMBL263638
SMILES [#6]-[#6@H](-[#6]-[#6@H]-1-[#6]-[#6](=[#6])-[#6](=O)-[#8]-1)-[#6@H]1-[#6]-[#6]-[#6@H]2\[#6](-[#6]-[#6]-[#6][C@]12[#6])=[#6]\[#6]=[#6]-1/[#6]-[#6@@H](-[#8])-[#6](=[#6])-[#6@H](-[#8])-[#6]-1
InChI Key InChIKey=NFEAURPDDCSCJD-GHLZQXTLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50292629
Affinity DataKi: 1nMAssay Description:Displacement of [3H]1alpha,25-(OH)2D3 from rat recombinant full length VDRMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Antagonist activity at human VDR in COS7 cells assessed as induction of transcriptional transactivation after 24 hrs by mouse osteopontin luciferase ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.700nMAssay Description:Displacement of [3H]1,25-(OH)2D3 from rat recombinant His-tagged VDR ligand-binding domain expressed in Escherichia coli BL21More data for this Ligand-Target Pair
Affinity DataEC50: 25nMAssay Description:Agonist activity at human VDR in COS7 cells assessed as induction of transcriptional transactivation after 24 hrs by mouse osteopontin luciferase rep...More data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Activity at rat recombinant full length VDR expressed in rat ROS 17/2.8 cells transfected with 24-hydroxylase gene promoter assessed as transcription...More data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist activity at human VDR in HEK293 cells assessed as induction of transcriptional transactivation after 24 hrs by mouse osteopontin luciferase r...More data for this Ligand-Target Pair