BDBM50292636 4-hexyl resorcinol::ACRISORCIN::CHEMBL443605

SMILES CCCCCCc1ccc(O)cc1O

InChI Key InChIKey=WFJIVOKAWHGMBH-UHFFFAOYSA-N

Data  1 KI  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50292636   

TargetTyrosinase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50292636(4-hexyl resorcinol | ACRISORCIN | CHEMBL443605)
Affinity DataKi:  3.90E+4nMAssay Description:Inhibition of human His-tagged tyrosinase expressed in HEK 293 cells using L-DOPA as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Università

Curated by ChEMBL
LigandPNGBDBM50292636(4-hexyl resorcinol | ACRISORCIN | CHEMBL443605)
Affinity DataIC50:  980nMAssay Description:Inhibition of mushroom tyrosine kinase assessed as oxidation of 0.25 mM L-3,4-dihydroxyphenylalanineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50292636(4-hexyl resorcinol | ACRISORCIN | CHEMBL443605)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 15-LO in human PMNL using arachidonic acid as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50292636(4-hexyl resorcinol | ACRISORCIN | CHEMBL443605)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of 5-LO in human PMNL using arachidonic acid as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50292636(4-hexyl resorcinol | ACRISORCIN | CHEMBL443605)
Affinity DataIC50:  9.40E+4nMAssay Description:Inhibition of human His-tagged tyrosinase expressed in HEK 293 cells using L-DOPA as substrate by MBTH based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50292636(4-hexyl resorcinol | ACRISORCIN | CHEMBL443605)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 12-LO in human PMNL using arachidonic acid preincubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Università

Curated by ChEMBL
LigandPNGBDBM50292636(4-hexyl resorcinol | ACRISORCIN | CHEMBL443605)
Affinity DataIC50:  610nMAssay Description:Inhibition of mushroom tyrosinase using TBC as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Università

Curated by ChEMBL
LigandPNGBDBM50292636(4-hexyl resorcinol | ACRISORCIN | CHEMBL443605)
Affinity DataIC50:  560nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as dopachrome formation after 5 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50292636(4-hexyl resorcinol | ACRISORCIN | CHEMBL443605)
Affinity DataIC50:  560nMAssay Description:Inhibition of tyrosinase (unknown origin) using L-DOPA as substrate assessed as formation of dopachrome by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50292636(4-hexyl resorcinol | ACRISORCIN | CHEMBL443605)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed