BDBM50292665 (+)-1-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidin-1-yl)ethanone::(+/-)-1-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidin-1-yl)ethanone::(-)-1-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidin-1-yl)ethanone::CHEMBL498556

SMILES CC(=O)N1CCCC(C1)(C1CCN(Cc2ccc(Br)cc2)CC1)c1ccccc1

InChI Key InChIKey=ZZNJOZRGMRQBSR-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50292665   

TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292665((+)-1-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidi...)
Affinity DataIC50:  140nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292665((+)-1-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidi...)
Affinity DataIC50:  140nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292665((+)-1-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidi...)
Affinity DataIC50:  2.31E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292665((+)-1-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to human muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292665((+)-1-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidi...)
Affinity DataIC50:  3.00E+3nMAssay Description:Binding affinity to human muscarinic M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292665((+)-1-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to human muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292665((+)-1-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidi...)
Affinity DataIC50:  1.00E+4nMAssay Description:Binding affinity to human muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292665((+)-1-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to human muscarinic M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292665((+)-1-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidi...)
Affinity DataIC50:  1.00E+4nMAssay Description:Binding affinity to human muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed