BDBM50292745 1-[(1-Phenylethyl)amino]ethaniminium bromide::CHEMBL448703

SMILES CC(\[NH+]=C(\C)N)c1ccccc1

InChI Key InChIKey=RUOJDRGEBFFDGE-UHFFFAOYSA-O

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50292745   

TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292745(1-[(1-Phenylethyl)amino]ethaniminium bromide | CHE...)
Affinity DataIC50:  450nMAssay Description:Inhibition of iNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline preincubated 1 hr b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292745(1-[(1-Phenylethyl)amino]ethaniminium bromide | CHE...)
Affinity DataIC50:  3.00E+5nMAssay Description:Inhibition of eNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline preincubated 1 hr b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Università

Curated by ChEMBL
LigandPNGBDBM50292745(1-[(1-Phenylethyl)amino]ethaniminium bromide | CHE...)
Affinity DataIC50:  450nMAssay Description:Inhibition of mouse macrophage iNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50292745(1-[(1-Phenylethyl)amino]ethaniminium bromide | CHE...)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of rat brain nNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Università

Curated by ChEMBL
LigandPNGBDBM50292745(1-[(1-Phenylethyl)amino]ethaniminium bromide | CHE...)
Affinity DataIC50:  3.00E+5nMAssay Description:Inhibition of bovine eNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed