BDBM50292909 (+/-)-trans-2-Hydroxy-3-(4-benzoylpiperidino)tetralin Hydrochloride::CHEMBL1186644::CHEMBL473546

SMILES O[C@@H]1Cc2ccccc2C[C@H]1N1CCC(CC1)C(=O)c1ccccc1

InChI Key InChIKey=CCUKDADSUYUFEE-NHCUHLMSSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50292909   

TargetVesicular acetylcholine transporter(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50292909((+/-)-trans-2-Hydroxy-3-(4-benzoylpiperidino)tetra...)
Affinity DataKi:  4.30nMAssay Description:Displacement of (-)-[3H]vesamicol from human VAChT expressed in rat PC12 cell membrane after 20 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVesicular acetylcholine transporter(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50292909((+/-)-trans-2-Hydroxy-3-(4-benzoylpiperidino)tetra...)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]vesamicol from human vesicular acetylcholine transporter expressed in rat PC12 cells by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Washington University

Curated by ChEMBL
LigandPNGBDBM50292909((+/-)-trans-2-Hydroxy-3-(4-benzoylpiperidino)tetra...)
Affinity DataKi:  220nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in guinea pig brain membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Washington University

Curated by ChEMBL
LigandPNGBDBM50292909((+/-)-trans-2-Hydroxy-3-(4-benzoylpiperidino)tetra...)
Affinity DataKi:  220nMAssay Description:Displacement of (+)- [3H]pentazocine from sigma 1 receptor expressed in guinea pig brain membrane homogenates by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed