BDBM50292928 (+/-)-N-benzyl-2-(1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)acetamide::CHEMBL490489

SMILES COc1ccc(CC2N(CC(=O)NCc3ccccc3)CCc3cc(OC)c(OC)cc23)cc1OC

InChI Key InChIKey=FYSUZYYFUUADES-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50292928   

TargetOrexin/Hypocretin receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50292928((+/-)-N-benzyl-2-(1-(3,4-dimethoxybenzyl)-6,7-dime...)
Affinity DataIC50: 119nMAssay Description:Antagonist activity at OX1R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50292928((+/-)-N-benzyl-2-(1-(3,4-dimethoxybenzyl)-6,7-dime...)
Affinity DataIC50: 119nMAssay Description:Inhibition of OX1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50292928((+/-)-N-benzyl-2-(1-(3,4-dimethoxybenzyl)-6,7-dime...)
Affinity DataIC50: 8.15E+3nMAssay Description:Antagonist activity at OX2R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50292928((+/-)-N-benzyl-2-(1-(3,4-dimethoxybenzyl)-6,7-dime...)
Affinity DataIC50: 8.15E+3nMAssay Description:Inhibition of OX2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed