BDBM50292970 (S)-N-((1-(2-amino-5-m-tolylthiazole-4-carbonyl)azetidin-2-yl)methyl)-6-chloroimidazo[2,1-b]thiazole-5-carboxamide::CHEMBL454133

SMILES Cc1cccc(c1)-c1sc(N)nc1C(=O)N1CC[C@H]1CNC(=O)c1c(Cl)nc2sccn12

InChI Key InChIKey=UPXYLINNYITONY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50292970   

TargetOrexin receptor type 2(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50292970((S)-N-((1-(2-amino-5-m-tolylthiazole-4-carbonyl)az...)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at OX2 receptor by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50292970((S)-N-((1-(2-amino-5-m-tolylthiazole-4-carbonyl)az...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at OX1 receptor by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed