BDBM50292984 1-[2-(4-([(3R,5S)-3,5-Dimethyl-1-piperazinyl]methyl)phenyl)-2-methylpropanoyl]-N-(4-fluorophenyl)-4-piperidinamine::CHEMBL489479

SMILES C[C@H]1CN(Cc2ccc(cc2)C(C)(C)C(=O)N2CCC(CC2)Nc2ccc(F)cc2)C[C@@H](C)N1

InChI Key InChIKey=HUZVCBYMIXTYBP-OYRHEFFESA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50292984   

TargetMotilin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50292984(1-[2-(4-([(3R,5S)-3,5-Dimethyl-1-piperazinyl]methy...)
Affinity DataEC50:  31.6nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells assessed as increase in intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50292984(1-[2-(4-([(3R,5S)-3,5-Dimethyl-1-piperazinyl]methy...)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli using diethoxyfluorescein substrate by time dependent inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed