BDBM50293006 2-amino-4-(2,3-dimethoxyphenyl)-5-oxo-7-phenyl-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile::CHEMBL460700

SMILES COc1cccc(C2C(C#N)C(=N)OC3=C2C(=O)CC(C3)c2ccccc2)c1OC

InChI Key InChIKey=KXWMABLGFVTSAK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293006   

TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50293006(2-amino-4-(2,3-dimethoxyphenyl)-5-oxo-7-phenyl-5,6...)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [3H]D-Asp from human EAAT2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50293006(2-amino-4-(2,3-dimethoxyphenyl)-5-oxo-7-phenyl-5,6...)
Affinity DataIC50:  5.01E+4nMAssay Description:Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50293006(2-amino-4-(2,3-dimethoxyphenyl)-5-oxo-7-phenyl-5,6...)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [3H]D-Asp from human EAAT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed