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BDBM50293038 (R)-N2-(4-Cyanobenzyl)-N1-(4-chlorophenyl)-N2-methylpyrrolidine-1,2-dicarboxamide::CHEMBL462435

SMILES: CN(Cc1ccc(cc1)C#N)C(=O)[C@H]1CCCN1C(=O)Nc1ccc(Cl)cc1

InChI Key: InChIKey=HUBAFHZHUSREPZ-TWYLJJHKNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293038   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-C chemokine receptor type 1


(Homo sapiens (Human))
BDBM50293038
PNG
((R)-N2-(4-Cyanobenzyl)-N1-(4-chlorophenyl)-N2-meth...)
Show SMILES CN(Cc1ccc(cc1)C#N)C(=O)[C@H]1CCCN1C(=O)Nc1ccc(Cl)cc1
Show InChI InChI=1/C21H21ClN4O2/c1-25(14-16-6-4-15(13-23)5-7-16)20(27)19-3-2-12-26(19)21(28)24-18-10-8-17(22)9-11-18/h4-11,19H,2-3,12,14H2,1H3,(H,24,28)/t19-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.30E+4n/an/an/an/an/an/a



Pharmacopeia Inc

Curated by ChEMBL


Assay Description
Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cells


J Med Chem 52: 1295-301 (2010)


Article DOI: 10.1021/jm801416q
BindingDB Entry DOI: 10.7270/Q25X28Z3
More data for this
Ligand-Target Pair