BDBM50293083 7-({[(2R/S)-2,4-Dihydroxybutyl](methyl)amino}methyl)-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one::CHEMBL453099

SMILES CN(CC(O)CCO)Cc1c[nH]c2c1nc[nH]c2=O

InChI Key InChIKey=XOFNJPVVVPIKSR-UHFFFAOYSA-N

Data  1 KI  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293083   

TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50293083(7-({[(2R/S)-2,4-Dihydroxybutyl](methyl)amino}methy...)
Affinity DataKi:  227nMAssay Description:Inhibition of human PNP by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50293083(7-({[(2R/S)-2,4-Dihydroxybutyl](methyl)amino}methy...)
Affinity DataKd:  227nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

US Patent
LigandPNGBDBM50293083(7-({[(2R/S)-2,4-Dihydroxybutyl](methyl)amino}methy...)
Affinity DataKd:  770nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In DepthDetails US Patent