BDBM50293171 (1R,2S,4S,6E,8S,11R,12R,13S,14R,15R,22R)-13-hydroxy-1',2,4,6,8,12,14,19-octamethyl-23,25,26,27-tetraoxaspiro[pentacyclo[18.5.1.1^{11,15}.0^{1,22}.0^{16,21}]heptacosane-24,4'-piperidine]-6,16(21),19-triene-17,18-dione::CHEMBL508232

SMILES C[C@H]1[C@H]2CC[C@H](C)\C=C(C)\C[C@@H](C)C[C@H](C)[C@]34OC5=C(C)C(=O)C(=O)C([C@H](O2)[C@H](C)[C@H]1O)=C5[C@H]3OC1(CCN(C)CC1)O4

InChI Key InChIKey=ZFTJWLAKRPKMHQ-WALJHCINSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293171   

TargetBcl-2-like protein 1(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293171((1R,2S,4S,6E,8S,11R,12R,13S,14R,15R,22R)-13-hydrox...)
Affinity DataKd:  3.77E+5nMAssay Description:Inhibition of interaction between GST-tagged Bcl-xl and Bak by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293171((1R,2S,4S,6E,8S,11R,12R,13S,14R,15R,22R)-13-hydrox...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of interaction between GST-tagged Bcl-xl and Bak by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293171((1R,2S,4S,6E,8S,11R,12R,13S,14R,15R,22R)-13-hydrox...)
Affinity DataKd:  3.99E+5nMAssay Description:Inhibition of interaction between Bcl-xl and Bak by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed