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BDBM50293475 (R)-4-((1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-yl)methyl)-N-(1-(4-iodophenyl)propyl)benzamide::CHEMBL563412

SMILES: CC[C@@H](NC(=O)c1ccc(CC2CCN(Cc3ccc4OCOc4c3)CC2)cc1)c1ccc(I)cc1

InChI Key: InChIKey=GWRAMEHAFVFMCA-HHHXNRCGSA-N

Data: 1 KI

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293475   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor


(Homo sapiens (Human))
BDBM50293475
PNG
((R)-4-((1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidi...)
Show SMILES CC[C@@H](NC(=O)c1ccc(CC2CCN(Cc3ccc4OCOc4c3)CC2)cc1)c1ccc(I)cc1
Show InChI InChI=1S/C30H33IN2O3/c1-2-27(24-8-10-26(31)11-9-24)32-30(34)25-6-3-21(4-7-25)17-22-13-15-33(16-14-22)19-23-5-12-28-29(18-23)36-20-35-28/h3-12,18,22,27H,2,13-17,19-20H2,1H3,(H,32,34)/t27-/m1/s1
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Similars

Article
PubMed
20n/an/an/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Binding affinity to MCH1 receptor


Eur J Med Chem 44: 2583-96 (2009)


Article DOI: 10.1016/j.ejmech.2009.01.031
BindingDB Entry DOI: 10.7270/Q2TH8MRK
More data for this
Ligand-Target Pair