BDBM50293516 2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)quinazolin-4-amine::2-(6-methylpyridin-2-yl)-N-pyridin-4-ylquinazolin-4-amine::CHEMBL570533

SMILES: Cc1cccc(n1)-c1nc(Nc2ccncc2)c2ccccc2n1

InChI Key: InChIKey=JONFDFIXMPXTRH-UHFFFAOYSA-N

Data: 3 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50293516   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 (Human)	BDBM50293516 (2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)quinazoli...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50293516 (2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)quinazoli...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50293516 (2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)quinazoli...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50293516 (2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)quinazoli...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair