BDBM50293528 1-(3-(5-(3,4-dimethoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl)-3-(2-fluoro-4-(trifluoromethyl)phenyl)urea::CHEMBL558867

SMILES COc1ccc(cc1OC)-c1cnc2[nH]cc(-c3cccc(NC(=O)Nc4ccc(cc4F)C(F)(F)F)c3)c2c1

InChI Key InChIKey=DBGGEZRNKYSCMN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293528   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293528(1-(3-(5-(3,4-dimethoxyphenyl)-1H-pyrrolo[2,3-b]pyr...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of GST-tagged human IGF1R expressed in Sf9-baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed