BDBM50293548 1-(3-(5-(1H-pyrrol-2-yl)-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl)-3-(2-phenoxyphenyl)urea::CHEMBL565235

SMILES O=C(Nc1cccc(c1)-c1c[nH]c2ncc(cc12)-c1ccc[nH]1)Nc1ccccc1Oc1ccccc1

InChI Key InChIKey=KRCWIMOFFZNJDN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293548   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293548(1-(3-(5-(1H-pyrrol-2-yl)-1H-pyrrolo[2,3-b]pyridin-...)
Affinity DataIC50:  7.46E+3nMAssay Description:Inhibition of IGF1-induced human IGF1R phosphorylation expressed in mouse NIH-3T3 cells treated 2 hrs prior to IGF1 challenge by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293548(1-(3-(5-(1H-pyrrol-2-yl)-1H-pyrrolo[2,3-b]pyridin-...)
Affinity DataIC50:  233nMAssay Description:Inhibition of GST-tagged human IGF1R expressed in Sf9-baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed