BDBM50293553 1-(3-(5-(3-(dimethylcarbamoyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl)-3-(4-phenoxyphenyl)urea::CHEMBL539152

SMILES CN(C)C(=O)c1cccc(c1)-c1cnc2[nH]cc(-c3cccc(NC(=O)Nc4ccc(Oc5ccccc5)cc4)c3)c2c1

InChI Key InChIKey=IKBKKXCYAVMTBB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293553   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293553(1-(3-(5-(3-(dimethylcarbamoyl)phenyl)-1H-pyrrolo[2...)
Affinity DataIC50:  3.07E+3nMAssay Description:Inhibition of IGF1-induced human IGF1R phosphorylation expressed in mouse NIH-3T3 cells treated 2 hrs prior to IGF1 challenge by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293553(1-(3-(5-(3-(dimethylcarbamoyl)phenyl)-1H-pyrrolo[2...)
Affinity DataIC50:  2.04E+3nMAssay Description:Inhibition of GST-tagged human IGF1R expressed in Sf9-baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed