BDBM50293592 4-(2-Aminothiazol-4-yl)phenol::4-(2-amino-1,3-thiazol-4-yl)phenol::CHEMBL483790

SMILES Nc1nc(cs1)-c1ccc(O)cc1

InChI Key InChIKey=QGSJYYIRAFRPIT-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50293592   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Decode Biostructures

Curated by ChEMBL
LigandPNGBDBM50293592(4-(2-Aminothiazol-4-yl)phenol | 4-(2-amino-1,3-thi...)
Affinity DataIC50:  1.44E+6nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetFructose-1,6-bisphosphatase 1(Sus scrofa (Pig))
Boston College

Curated by ChEMBL
LigandPNGBDBM50293592(4-(2-Aminothiazol-4-yl)phenol | 4-(2-amino-1,3-thi...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
A*Star

Curated by ChEMBL
LigandPNGBDBM50293592(4-(2-Aminothiazol-4-yl)phenol | 4-(2-amino-1,3-thi...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 (unknown origin) (72 to 385 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
A*Star

Curated by ChEMBL
LigandPNGBDBM50293592(4-(2-Aminothiazol-4-yl)phenol | 4-(2-amino-1,3-thi...)
Affinity DataIC50:  5.70E+4nMAssay Description:Inhibition of N-terminal GST-tagged MNK1 (unknown origin) (37 to 341 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Decode Biostructures

Curated by ChEMBL
LigandPNGBDBM50293592(4-(2-Aminothiazol-4-yl)phenol | 4-(2-amino-1,3-thi...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB