BDBM50293598 2'-des-methyl indomethacin::CHEMBL503179::US9346803, Des-methylIndomethacin

SMILES: COc1ccc2c(c1)c(cn2C(=O)c3ccc(cc3)Cl)CC(=O)O

InChI Key: InChIKey=DHEMTWWLRLOBKI-UHFFFAOYSA-N

Data: 11 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50293598   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldo-keto reductase family 1 member C3 (Human)	BDBM50293598 (2'-des-methyl indomethacin | CHEMBL503179 | US9346...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.960	n/a	n/a	n/a	n/a	n/a	n/a
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Aldo-keto reductase family 1 member C1 (Human)	BDBM50293598 (2'-des-methyl indomethacin | CHEMBL503179 | US9346...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
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Aldo-keto reductase family 1 member C2 (Human)	BDBM50293598 (2'-des-methyl indomethacin | CHEMBL503179 | US9346...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
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Aldo-keto reductase family 1 member C4 (Human)	BDBM50293598 (2'-des-methyl indomethacin | CHEMBL503179 | US9346...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	48.7	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 1 (Human)	BDBM50293598 (2'-des-methyl indomethacin | CHEMBL503179 | US9346...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Mouse)	BDBM50293598 (2'-des-methyl indomethacin | CHEMBL503179 | US9346...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 1 (Human)	BDBM50293598 (2'-des-methyl indomethacin | CHEMBL503179 | US9346...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aldo-keto reductase family 1 member C4 (Human)	BDBM50293598 (2'-des-methyl indomethacin | CHEMBL503179 | US9346...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.87E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member C1 (Human)	BDBM50293598 (2'-des-methyl indomethacin | CHEMBL503179 | US9346...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member C2 (Human)	BDBM50293598 (2'-des-methyl indomethacin | CHEMBL503179 | US9346...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member C3 (Human)	BDBM50293598 (2'-des-methyl indomethacin | CHEMBL503179 | US9346...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair