BDBM50293675 CHEMBL549322::N-(5-methyl-1H-pyrazol-3-yl)-2-(phenylthio)quinazolin-4-amine

SMILES Cc1cc(Nc2nc(Sc3ccccc3)nc3ccccc23)[nH]n1

InChI Key InChIKey=QITTZHVXBHDUGY-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50293675   

TargetAurora kinase A(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293675(CHEMBL549322 | N-(5-methyl-1H-pyrazol-3-yl)-2-(phe...)
Affinity DataKi:  20nMAssay Description:Inhibition of Aurora-A by coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293675(CHEMBL549322 | N-(5-methyl-1H-pyrazol-3-yl)-2-(phe...)
Affinity DataKi:  171nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293675(CHEMBL549322 | N-(5-methyl-1H-pyrazol-3-yl)-2-(phe...)
Affinity DataKi:  590nMAssay Description:Inhibition of Aurora-BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293675(CHEMBL549322 | N-(5-methyl-1H-pyrazol-3-yl)-2-(phe...)
Affinity DataKi:  800nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed